Histopathological Changes in Rat Organ following Ingestion of Crude Oil Contaminated Diet

Histopathological Changes in Rat Organ following Ingestion of Crude Oil Contaminated Diet

*1Onifade, A.O., 2Ologunde, M.O. and 1Ariyo, O.
1Department of Food Science and Technology, Wesley University of Food Science and Technology, Ondo.
2Department of Food Science and Engineering, Ladoke Akintola University of Science and Technology, Ogbomosho
*Corresponding author: sholaernest@yahoo.com

Accepted on April 29, 2014

Abstract
The possible effects which crude oil polluted foods may have on specific organs of mammals like the kidney, liver, small intestine, spleen and heart were investigated using white male wistar rats. Four formulated diets (including a control) depicting different levels of crude oil contaminated cassava/fish meal diets were used as experimental meal in an animal and bioassay work. The result revealed a considerable negative effect that crude oil had on the organs of the experimental animals as against that of control. Hispathological investigation showed the level of damage done to the organs which ranged from shrunken villi, oedema in the small intestine to the glomeruli and tubules in the kidney.

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